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EPB41L4B Polyklonaler Antikörper

EPB41L4B Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31669-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using EPB41L4B Polyclonal antibody (31669-1-AP)

    WB analysis using 31669-1-AP (same clone as 31669-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31669-1-AP (EPB41L4B antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31669-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31669-1-PBS bindet in WB, Indirect ELISA EPB41L4B und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen EPB41L4B fusion protein Ag36353
Vollständiger Name erythrocyte membrane protein band 4.1 like 4B
Berechnetes Molekulargewicht99kDa
Beobachtetes Molekulargewicht100 kDa
GenBank-ZugangsnummerNM_00138562
Gene symbol EPB41L4B
Gene ID (NCBI) 54566
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The 4.1 proteins, encoded by the EPB41 (erythrocyte protein band 4.1) genes, are components of the cortical cytoskeleton underlying the cell membrane. The family of 4.1 proteins consists of the eponymous 4.1R protein first identified in erythrocytes (gene: EPB41), 4.1N (EPB41L1), 4.1G (EPB41L2), 4.1B (EPB41L3) as well as the less closely related members NBL4 (EPB41L4A), EHM2 (EPB41L4B) and EPB41L5 (EPB41L5). EHM2 is conspicuous in tumor cells with high migratory potential, such as metastatic melanoma and fibrosarcoma cells. In prostate cancer, EHM2 has been reported to be overexpressed and to diminish adhesion of prostate cancer cells to collagen. (PMID: 20860828)