EPCR/CD201 Rekombinanter Antikörper

EPCR/CD201 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

241853A7

Kat-Nr. : 98248-1-PBS

Synonyme

Centrosomal protein CCD41, Centrocyclin, CD201, APC receptor, Activated protein C receptor

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  FC experiment of bEnd.3 using 98248-1-RR (same clone as 98248-1-PBS)

  1x10^6 bEnd.3 cells were surface stained with 0.25 ug Anti-Mouse EPCR/CD201 Rabbit Recombinant Antibody (98248-1-RR, Clone: 241853A7) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (red), or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (blue). Cells were not fixed. This data was developed using the same antibody clone with 98248-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98248-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98248-1-RR against Mouse EPCR/CD201 were performed. The affinity constant is 52.5 pM.

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Geprüfte Anwendungen

Produktinformation

98248-1-PBS bindet in FC EPCR/CD201 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: protein C receptor, endothelial
• Berechnetes Molekulargewicht: 27kDa
• GenBank-Zugangsnummer: NM_011171.2
• Gene symbol: PROCR
• Gene ID (NCBI): 19124
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

EPCR, also known as CD201, protein C receptor (PROCR), or activated protein C receptor (APC receptor), is a transmembrane glycoprotein. EPCR promotes the activation of protein C, which has anticoagulant and cytoprotective effects. EPCR facilitates the activation of protein C by the thrombin-thrombomodulin complex but also facilitates APC-mediated cytoprotective effects on cells that involve the activation of protease-activated receptors (PAR) 1 and 3(PMID: 27207424).