EPCR/CD201 Rekombinanter Antikörper

EPCR/CD201 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

241853A7

Kat-Nr. : 98248-1-RR

Synonyme

Centrosomal protein CCD41, Centrocyclin, CD201, APC receptor, Activated protein C receptor

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  FC experiment of bEnd.3 using 98248-1-RR

  1x10^6 bEnd.3 cells were surface stained with 0.25 ug Anti-Mouse EPCR/CD201 Rabbit Recombinant Antibody (98248-1-RR, Clone: 241853A7) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (red), or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (blue). Cells were not fixed.

• 

  Affinity and Kinetic Characterization of 98248-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98248-1-RR against Mouse EPCR/CD201 were performed. The affinity constant is 52.5 pM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: bEnd.3-Zellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98248-1-RR bindet in FC EPCR/CD201 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: protein C receptor, endothelial
• Berechnetes Molekulargewicht: 27kDa
• GenBank-Zugangsnummer: NM_011171.2
• Gene symbol: PROCR
• Gene ID (NCBI): 19124
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

EPCR, also known as CD201, protein C receptor (PROCR), or activated protein C receptor (APC receptor), is a transmembrane glycoprotein. EPCR promotes the activation of protein C, which has anticoagulant and cytoprotective effects. EPCR facilitates the activation of protein C by the thrombin-thrombomodulin complex but also facilitates APC-mediated cytoprotective effects on cells that involve the activation of protease-activated receptors (PAR) 1 and 3(PMID: 27207424).