EPCR/CD201 Rekombinanter Antikörper

EPCR/CD201 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

CoraLite® Plus 647 Fluorescent Dye

CloneNo.

241853A7

Kat-Nr. : CL647-98248

Synonyme

241853A7, Activated protein C receptor, APC receptor, CD201, Centrocyclin

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  FC experiment of bEnd.3 using CL647-98248

  1x10^6 bEnd.3 cells were surface stained with 0.25 ug CoraLite® Plus 647 Anti-Mouse EPCR/CD201 Rabbit RecAb (CL647-98248, Clone: 241853A7)(red) or 0.25 ug CoraLite® Plus 647 Rabbit IgG Isotype Control RecAb (CL647-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: bEnd.3-Zellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

CL647-98248 bindet in FC EPCR/CD201 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: EPCR/CD201 fusion protein Eg1517
• Vollständiger Name: protein C receptor, endothelial
• Berechnetes Molekulargewicht: 27kDa
• GenBank-Zugangsnummer: NM_011171.2
• Gene symbol: PROCR
• Gene ID (NCBI): 19124
• Konjugation: CoraLite® Plus 647 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 654 nm / 674 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

EPCR, also known as CD201, protein C receptor (PROCR), or activated protein C receptor (APC receptor), is a transmembrane glycoprotein. EPCR promotes the activation of protein C, which has anticoagulant and cytoprotective effects. EPCR facilitates the activation of protein C by the thrombin-thrombomodulin complex but also facilitates APC-mediated cytoprotective effects on cells that involve the activation of protease-activated receptors (PAR) 1 and 3(PMID: 27207424).