EPCR/CD201 Rekombinanter Antikörper

EPCR/CD201 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

PE Fluorescent Dye

CloneNo.

241806D7

Kat-Nr. : PE-FcA98325

Synonyme

CD201, EPCR, PROCR, Activated protein C receptor, APC receptor

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  FC experiment of HUVEC using PE-FcA98325

  1x10^6 HUVEC cells (left) or Jurkat cells (right) were surface stained with 5 ul PE Anti-Human EPCR/CD201 Rabbit RecAb (PE-FcA98325, Clone: 241806D7) (red) or PE Rabbit IgG Isotype Control RecAb (PE-FcA98136, Clone: 240953C9) (blue). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: HUVEC-Zellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Produktinformation

PE-FcA98325 bindet in FC EPCR/CD201 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: EPCR/CD201 fusion protein Eg2339
• Vollständiger Name: protein C receptor, endothelial (EPCR)
• Berechnetes Molekulargewicht: 238 aa, 27 kDa
• GenBank-Zugangsnummer: BC014451
• Gene symbol: PROCR
• Gene ID (NCBI): 10544
• Konjugation: PE Fluorescent Dye
• Excitation/Emission maxima wavelengths: 496 nm, 565 nm / 578 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

EPCR (endothelial cell protein C receptor), also known as CD201, is a type 1 transmembrane protein that is primarily found on endothelial cells. It exhibits sequence and three-dimensional structural homology with the major histocompatibility class 1/CD1 family of proteins, particularly CD1d. It binds activated protein C and enhances protein C activation by the thrombin-thrombomodulin complex. It plays a role in the protein C pathway controlling blood coagulation.