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EPDR1 Polyklonaler Antikörper

EPDR1 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27252-1-PBS

Synonyme

EPDR, Mammalian ependymin-related protein 1, MERP 1, MERP1, MERP-1

Filter:
  • Western Blot (WB) analysis of various lysates using EPDR1 Polyclonal antibody (27252-1-AP)

    WB analysis using 27252-1-AP (same clone as 27252-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27252-1-AP (EPDR1 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27252-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human stomach tissue using EPDR1 Polyclonal antibody (27252-1-AP)

    IHC staining of human stomach using 27252-1-AP (same clone as 27252-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 27252-1-AP (EPDR1 antibody) at dilution of 1:2000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27252-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27252-1-PBS bindet in WB, IHC, Indirect ELISA EPDR1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen EPDR1 fusion protein Ag26120
Vollständiger Name Mammalian ependymin-related protein 1
Berechnetes Molekulargewicht 25 kDa
Beobachtetes Molekulargewicht25-30 kDa
GenBank-ZugangsnummerBC018299
Gene symbol EPDR1
Gene ID (NCBI) 54749
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The ependymin-related 1 (EPDR1) gene, also known as MERP1 and UCC1, encodes for a protein related to ependymins, which are type II transmembrane proteins that are similar to two families of cell adhesion molecules: the protocadherins and ependymins. Ependymin-related protein 1 (EPDR1) was recently identified as a secreted human batokine regulating mitochondrial respiration linked to thermogenesis in brown fat. Proteomics studies of mammalian mannose-6-phosphate (M6P) glycoproteins have identified EPDR1 as a lysosomal protein with unknown function. The lysosomal localization of EPDR1 was further demonstrated in mouse brain homogenates by subcellular fractionation.(PMID: 36343918, PMID: 33902536, PMID: 30729188)