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EPOR Rekombinanter Antikörper

EPOR Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250056D4

Kat-Nr. : 85901-1-PBS

Synonyme

EPO-R, Erythropoietin receptor

Filter:
  • Western Blot (WB) analysis of various lysates using EPOR Recombinant antibody (85901-1-RR)

    WB analysis using 85901-1-RR (same clone as 85901-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85901-1-RR (EPOR antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85901-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85901-1-PBS bindet in WB, Indirect ELISA EPOR und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen EPOR fusion protein Eg2711
Vollständiger Name erythropoietin receptor
Berechnetes Molekulargewicht55 kDa
Beobachtetes Molekulargewicht73 kDa
GenBank-ZugangsnummerNM_010149.3
Gene symbol Epor
Gene ID (NCBI) 13857
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Erythropoietin (EPO) receptor (EPOR) is a glycoprotein that belongs to the type I superfamily of single-transmembrane cytokine receptors. It consists of an extracellular domain that binds to the EPO ligand, a transmembrane domain and an intracellular domain. The interaction of EPO and EPOR triggers the activation of several signaling pathways that induce erythropoiesis, including JAK2/STAT5, PI3K/AKT, and MAPK (PMID: 34281163). EPOR is present on erythroid progenitor cells and has also been detected on a wide variety of non-hematopoietic cells (PMID: 36233351). The calculated molecular weight of EPOR is 55 kDa. EPOR undergoes posttranslational modification and the apparent molecular weight of 66-78 kDa has been reported (PMID: 8943308; 12088257).