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ERBB3 Polyklonaler Antikörper

ERBB3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30452-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using ERBB3 Polyclonal antibody (30452-1-AP)

    WB analysis using 30452-1-AP (same clone as 30452-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30452-1-AP (ERBB3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30452-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30452-1-PBS bindet in WB, Indirect ELISA ERBB3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ERBB3 fusion protein Ag30713
Vollständiger Name v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Beobachtetes Molekulargewicht200 kDa
GenBank-ZugangsnummerBC082992
Gene symbol ERBB3
Gene ID (NCBI) 2065
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (ErbB-3, HER3) is a member of the EGF receptor tyrosine kinase family including EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3), and ErbB-4 (HER4) that are frequently overexpressed in a variety of carcinomas. These family members form either homodimers or heterodimers upon ligand binding to mediate cell growth. ErbB-3 binds and is activated by neuregulins and NTAK. It forms a heterodimer with each of the other ErbB receptors. ErbB-3 is predominantly expressed in epithelial tissues and the brain and is overexpressed in a subset of human mammary tumors.