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ERC1 Monoklonaler Antikörper

ERC1 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2A5B9

Kat-Nr. : 66681-1-PBS

Synonyme

Cast2, ELKS, ERC 1, ERC1, KIAA1081, Rab6 interacting protein 2, RAB6IP2

Filter:
  • Western Blot (WB) analysis of various lysates using ERC1 Monoclonal antibody (66681-1-Ig)

    WB analysis using 66681-1-Ig (same clone as 66681-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66681-1-Ig (ERC1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66681-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

66681-1-PBS bindet in WB, Indirect ELISA ERC1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen ERC1 fusion protein Ag17665
Vollständiger Name ELKS/RAB6-interacting/CAST family member 1
Berechnetes Molekulargewicht 1116 aa, 128 kDa
Beobachtetes Molekulargewicht 135 kDa
GenBank-ZugangsnummerBC132782
Gene symbol ERC1
Gene ID (NCBI) 23085
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ERC is an acronym based on previous separate namings of members of this protein family, ELKS, Rab6IP2 and CAST (PMID: 12391317). They are known to bind RIMs, the active zone proteins that regulate neurotransmitter release. ERC1 (ELKS) is an essential regulatory subunit of the IKK complex and likely functions by recruiting IκBα to the complex (PMID: 15218148). Multiple isoforms of ERC1 mRNA are generated by alternative splicing (PMID: 12203787). There are two known splice variants of ERC1 protein that differ at their C termini, ERC1a and ERC1b. ERC1a is ubiquitously expressed, whereas ERC1b is brain-specific (PMID: 12391317; 12923177).