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ERCC6 Rekombinanter Antikörper

ERCC6 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250645D4

Kat-Nr. : 86144-1-PBS

Synonyme

ARMD5, ATP dependent helicase ERCC6, Chimeric CSB-PGBD3 protein, Chimeric ERCC6-PGBD3 protein, CKN2

Filter:
  • Western Blot (WB) analysis of HeLa cells using ERCC6 Recombinant antibody (86144-1-RR)

    WB analysis of HeLa using 86144-1-RR (same clone as 86144-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 86144-1-RR (ERCC6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86144-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86144-1-PBS bindet in WB, Indirect ELISA ERCC6 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen ERCC6 fusion protein Ag18009
Vollständiger Name excision repair cross-complementing rodent repair deficiency, complementation group 6
Berechnetes Molekulargewicht 1493 aa, 168 kDa
Beobachtetes Molekulargewicht180 kDa
GenBank-ZugangsnummerBC127104
Gene symbol ERCC6/CSB
Gene ID (NCBI) 2074
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ERCC6, also named as CSB, belongs to the SNF2/RAD54 helicase family. It is involved in the preferential repair of active genes. It is presumed DNA or RNA unwinding function. ERCC6 corrects the UV survival and RNA synthesis after UV exposure of Cockayne syndrome complementation group B. Defects in ERCC6 are the cause of Cockayne syndrome type B (CSB) , cerebro-oculo-facio-skeletal syndrome type 1 (COFS1), De Sanctis-Cacchione syndrome (DSC), and UV-sensitive syndrome (UVS). Genetic variation in ERCC6 is associated with susceptibility to age-related macular degeneration type 5 (ARMD5). The antibody is specific to ERCC6.