ESPN Polyklonaler Antikörper

ESPN Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 20717-1-PBS

Synonyme

LP2654, Espin, DFNB36

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  WB analysis using 20717-1-AP (same clone as 20717-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20717-1-AP (ESPN antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20717-1-PBS in a different storage buffer formulation.

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  WB analysis of Neuro-2a using 20717-1-AP (same clone as 20717-1-PBS)

  Neuro-2a cells were subjected to SDS PAGE followed by western blot with 20717-1-AP (ESPN antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20717-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary cancer using 20717-1-AP (same clone as 20717-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 20717-1-AP (ESPN antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20717-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

20717-1-PBS bindet in WB, IHC, Indirect ELISA ESPN und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: espin
• Berechnetes Molekulargewicht: 92 kDa
• Beobachtetes Molekulargewicht: 30-33 kDa, 110 kDa
• GenBank-Zugangsnummer: NM_031475
• Gene symbol: ESPN
• Gene ID (NCBI): 83715
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ESPN, also named as DFNB36, is a multifunctional actin-bundling protein. ESPN plays a major role in regulating the organization, dimensions, dynamics and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in variouS mechanosensory and chemosensory cells. Defects in ESPN are the cause of deafness autosomal recessive type 36 (DFNB36). Defects in ESPN are the cause of deafness autosomal dominant without vestibular involvement (DFNAWVI). The antibody is specific to ESPN.