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ESS2/DGCR14 Polyklonaler Antikörper

ESS2/DGCR14 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 33574-1-PBS

Synonyme

DGCR14, ESS2, DGCR13, DGSH, DGS-H

Filter:
  • Western Blot (WB) analysis of various lysates using ESS2/DGCR14 Polyclonal antibody (33574-1-AP)

    WB analysis using 33574-1-AP (same clone as 33574-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33574-1-AP ( DGCR14 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33574-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

33574-1-PBS bindet in WB, Indirect ELISA ESS2/DGCR14 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ESS2/DGCR14 fusion protein Ag37915
Vollständiger Name DiGeorge syndrome critical region gene 14
Berechnetes Molekulargewicht476aa, 53 kDa
Beobachtetes Molekulargewicht 50-60 kDa
GenBank-ZugangsnummerNM_022719
Gene symbol DGCR14
Gene ID (NCBI) 8220
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ESS2 splicing factor homolog (ESS2), also named DiGeorge-syndrome critical region 14 (DGCR14), acts as a transcriptional co-activator for retinoic acid receptor-related orphan nuclear receptor gamma/gamma-t (Rorγ/γt). Ess2 is a nuclear protein with a coiled-coil domain [6] that is conserved from yeasts to humans. ESS2 is a member of the deletion gene cluster in the 22q11.2 deletion syndrome (22q11.2DS, also known as DiGeorge syndrome or CATCH 22 syndrome). The syndrome is characterized by varying defects of the heart, thymus and parathyroid glands.