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EVI2B Polyklonaler Antikörper

EVI2B Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24891-1-PBS

Synonyme

CD361, D17S376, EVDB, EVI 2B, EVI-2B

Filter:
  • Western Blot (WB) analysis of HepG2 cells using EVI2B Polyclonal antibody (24891-1-AP)

    WB analysis of HepG2 using 24891-1-AP (same clone as 24891-1-PBS)

    HepG2 cells were subjected to SDS PAGE followed by western blot with 24891-1-AP (EVI2B Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24891-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of A549 cells using EVI2B Polyclonal antibody (24891-1-AP)

    WB analysis of A549 using 24891-1-AP (same clone as 24891-1-PBS)

    A549 cells were subjected to SDS PAGE followed by western blot with 24891-1-AP (EVI2B Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24891-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using EVI2B Polyclonal antibody (24891-1-AP)

    IHC staining of human tonsillitis using 24891-1-AP (same clone as 24891-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 24891-1-AP (EVI2B antibody) at dilution of 1:1600 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24891-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using EVI2B Polyclonal antibody (24891-1-AP)

    IHC staining of human tonsillitis using 24891-1-AP (same clone as 24891-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 24891-1-AP (EVI2B antibody) at dilution of 1:1600 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24891-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

24891-1-PBS bindet in WB, IHC, Indirect ELISA EVI2B und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen EVI2B fusion protein Ag19511
Vollständiger Name ecotropic viral integration site 2B
Berechnetes Molekulargewicht 448 aa, 49 kDa
Beobachtetes Molekulargewicht 65 kDa
GenBank-ZugangsnummerBC005926
Gene symbol EVI2B
Gene ID (NCBI) 2124
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Ecotropic viral integration site 2B protein (EVI2B) is a type I transmembrane protein embedded within intron 27b of the neurofibromatosis type 1 (NF1) gene. It is transcribed in the opposite direction to the NF1 gene (PMID: 37584733). EVI2B is a downstream target of CCAAT/enhancer binding protein alpha (C/EBPα), which is crucial for myeloid differentiation and the function of hematopoietic progenitors (PMID: 36830696). This protein is highly expressed in mature granulocytes and is involved in the regulation of immune cell maturation (PMID: 28186500).