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EVI2B Rekombinanter Antikörper

EVI2B Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250344C9

Kat-Nr. : 85943-1-PBS

Synonyme

CD361, D17S376, EVDB, EVI 2B, EVI-2B

Filter:
  • Western Blot (WB) analysis of various lysates using EVI2B Recombinant antibody (85943-1-RR)

    WB analysis using 85943-1-RR (same clone as 85943-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85943-1-RR (EVI2B antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85943-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of THP-1 cells using EVI2B Recombinant antibody (85943-1-RR)

    IF Staining of THP-1 using 85943-1-RR (same clone as 85943-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using EVI2B antibody (85943-1-RR, Clone: 250344C9 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 85943-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85943-1-PBS bindet in WB, IF/ICC, Indirect ELISA EVI2B und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen EVI2B fusion protein Eg3709
Vollständiger Name ecotropic viral integration site 2B
Berechnetes Molekulargewicht 448 aa, 49 kDa
Beobachtetes Molekulargewicht60 kDa
GenBank-ZugangsnummerBC005926
Gene symbol EVI2B
Gene ID (NCBI) 2124
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Ecotropic viral integration site 2B protein (EVI2B) is a type I transmembrane protein embedded within intron 27b of the neurofibromatosis type 1 (NF1) gene. It is transcribed in the opposite direction to the NF1 gene (PMID: 37584733). EVI2B is a downstream target of CCAAT/enhancer binding protein alpha (C/EBPα), which is crucial for myeloid differentiation and the function of hematopoietic progenitors (PMID: 36830696). This protein is highly expressed in mature granulocytes and is involved in the regulation of immune cell maturation (PMID: 28186500).