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EXO1/Exonuclease 1 Monoklonaler Antikörper

EXO1/Exonuclease 1 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2D11D1

Kat-Nr. : 68536-1-PBS

Synonyme

EXO1, EC:3.1.-.-, EXOI, Exonuclease 1, Exonuclease I

Filter:
  • Western Blot (WB) analysis of various lysates using EXO1/Exonuclease 1 Monoclonal antibody (68536-1-Ig)

    WB analysis using 68536-1-Ig (same clone as 68536-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68536-1-Ig (EXO1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68536-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68536-1-PBS bindet in WB, Indirect ELISA EXO1/Exonuclease 1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen EXO1/Exonuclease 1 fusion protein Ag9253
Vollständiger Name exonuclease 1
Berechnetes Molekulargewicht 94 kDa
Beobachtetes Molekulargewicht 115-120 kDa
GenBank-ZugangsnummerBC007491
Gene symbol EXO1
Gene ID (NCBI) 9156
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

EXO1, also named as HEX1, is a 846 amino acid protein, which belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily. EXO1 is highly expressed in bone marrow, testis and thymus and at lower levels in colon, lymph nodes, ovary, placenta, prostate, small intestine, spleen and stomach. EXO1 as 5'->3' double-stranded DNA exonuclease, which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. EXO1 functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. The calculated molecular weight of EXO1 is 94 kDa, but the modified EXO1 protein is about 115 kDa.