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Endoglin/CD105 Rekombinanter Antikörper

Endoglin/CD105 Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241196G9

Kat-Nr. : 82993-6-PBS

Synonyme

CD105, 241196G9, HHT1, ENG, Endoglin

Filter:
  • Western Blot (WB) analysis of various lysates using Endoglin/CD105 Recombinant antibody (82993-6-RR)

    WB analysis using 82993-6-RR (same clone as 82993-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82993-6-RR (Endoglin/CD105 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82993-6-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human ovary cancer tissue using Endoglin/CD105 Recombinant antibody (82993-6-RR)

    IHC staining of human ovary cancer using 82993-6-RR (same clone as 82993-6-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 82993-6-RR (Endoglin/CD105 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 82993-6-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

82993-6-PBS bindet in WB, IHC, Indirect ELISA Endoglin/CD105 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name endoglin
Berechnetes Molekulargewicht 71 kDa
Beobachtetes Molekulargewicht75-90 kDa
GenBank-ZugangsnummerBC014271
Gene symbol CD105
Gene ID (NCBI) 2022
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)