Endoglin/CD105 Rekombinanter Antikörper

Endoglin/CD105 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

CoraLite® Plus 750 Fluorescent Dye

CloneNo.

230047E5

Kat-Nr. : CL750-98013

Synonyme

CD105, 230047E5, HHT1, ENG, Endoglin

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  FC experiment of human PBMCs using CL750-98013

  1x10^6 human PBMCs were surface stained with 5 ul CoraLite® Plus 750 Anti-Human Endoglin/CD105 Rabbit Recombinant Antibody (CL750-98013, Clone:230047E5), or Isotype Control. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  FC experiment of human PBMCs using CL750-98013

  1x10^6 human PBMCs were surface stained with 5 ul CoraLite® Plus 750 Anti-Human Endoglin/CD105 Rabbit Recombinant Antibody (CL750-98013, Clone:230047E5)(red), or Isotype Control (blue). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: humane PBMCs

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Produktinformation

CL750-98013 bindet in FC Endoglin/CD105 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: endoglin
• Berechnetes Molekulargewicht: 71 kDa
• GenBank-Zugangsnummer: BC014271
• Gene symbol: CD105
• Gene ID (NCBI): 2022
• Konjugation: CoraLite® Plus 750 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 755 nm / 780 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodeling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)