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Exportin 4 Polyklonaler Antikörper

Exportin 4 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25373-1-PBS

Synonyme

XPO4, Exp4, Exportin-4, KIAA1721

Filter:
  • Western Blot (WB) analysis of various lysates using Exportin 4 Polyclonal antibody (25373-1-AP)

    WB analysis using 25373-1-AP (same clone as 25373-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25373-1-AP (Exportin 4 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25373-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HEK-293 cells using Exportin 4 Polyclonal antibody (25373-1-AP)

    WB analysis of HEK-293 using 25373-1-AP (same clone as 25373-1-PBS)

    WB result of Exportin 4 antibody (25373-1-AP; 1:600; incubated at room temperature for 1.5 hours) with sh-Control and sh-Exportin 4 transfected HEK-293 cells. This data was developed using the same antibody clone with 25373-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse liver tissue using Exportin 4 Polyclonal antibody (25373-1-AP)

    IHC staining of mouse liver using 25373-1-AP (same clone as 25373-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 25373-1-AP (Exportin 4 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25373-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse liver tissue using Exportin 4 Polyclonal antibody (25373-1-AP)

    IHC staining of mouse liver using 25373-1-AP (same clone as 25373-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 25373-1-AP (Exportin 4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25373-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

25373-1-PBS bindet in WB, IHC, Indirect ELISA Exportin 4 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Exportin 4 fusion protein Ag21845
Vollständiger Name exportin 4
Berechnetes Molekulargewicht 1151 aa, 130 kDa
Beobachtetes Molekulargewicht127 kDa
GenBank-ZugangsnummerBC113571
Gene symbol Exportin 4/XPO4
Gene ID (NCBI) 64328
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

exportin 4 (XPO4) maps to chromosome 13q and belongs to the importin β family which acts as a bidirectional nuclear transport receptor. Decreased XPO4 expression has been shown to associate with hepatocellular carcinoma. A genome-wide copy number variation (CNV) association study in a small cohort of Malaysian subjects identified a CNV in XPO4 to be correlated with the progression of metabolic (dysfunction) associated fatty liver disease (MAFLD). (PMID: 34388518)