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F2RL3 Rekombinanter Antikörper

F2RL3 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250132A3

Kat-Nr. : 86509-1-PBS

Synonyme

Coagulation factor II receptor-like 3, PAR 4, PAR4, PAR-4, Proteinase activated receptor 4

Filter:
  • Western Blot (WB) analysis of various lysates using F2RL3 Recombinant antibody (86509-1-RR)

    WB analysis using 86509-1-RR (same clone as 86509-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86509-1-RR (F2RL3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86509-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86509-1-RR

    Affinity and Kinetic Characterization of 86509-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86509-1-RR against Human F2RL3 were performed. The affinity constant is 22.3 nM.

Geprüfte Anwendungen

Produktinformation

86509-1-PBS bindet in WB, Indirect ELISA F2RL3 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen F2RL3 fusion protein Ag13624
Vollständiger Name coagulation factor II (thrombin) receptor-like 3
Berechnetes Molekulargewicht 385 aa, 41 kDa
Beobachtetes Molekulargewicht 45 kDa
GenBank-ZugangsnummerBC074782
Gene symbol F2RL3
Gene ID (NCBI) 9002
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Coagulation factor II receptor-like 3 (F2RL3) encodes a member of the protease-activated receptor subfamily, also known as protease-activated receptor 4 (PAR4), which takes partin platelet activation, intimal hyperplasia and inflammation (PMID:34284820). An absence of PAR4 in mouse models results in impaired hemostasis and a protection against pulmonary embolism, and a small number of missense coding variants in F2RL3 that alter platelet aggregation and function have been described(PMID:35012325).