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Factor IX/PTC Polyklonaler Antikörper

Factor IX/PTC Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21481-1-PBS

Synonyme

F9, Factor IX, EC:3.4.21.22, Coagulation factor IXa light chain, Coagulation factor IXa heavy chain



Geprüfte Anwendungen

Produktinformation

21481-1-PBS bindet in WB, IHC, Indirect ELISA Factor IX/PTC und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Factor IX/PTC fusion protein Ag15723
Vollständiger Name coagulation factor IX
Berechnetes Molekulargewicht 461 aa, 52 kDa
Beobachtetes Molekulargewicht 56 kDa
GenBank-ZugangsnummerBC109215
Gene symbol F9
Gene ID (NCBI) 2158
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The F9 gene encodes coagulation factor IX, which circulates as an inactive zymogen until proteolytic release of its activation peptide allows it to assume the conformation of an active serine protease. Its role in the blood coagulation cascade is to activate factor X (F10) through interactions with calcium, membrane phospholipids, and factor VIII (F8). Factor IX and factor X both consist of 2 polypeptide chains referred to as the L (light) and H (heavy) chains. The H chain bears a structural resemblance to the polypeptide chain of the pancreatic serine protease trypsin (PRSS1). The L chain is covalently linked to the H chain by a single disulfide bond.