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FAAP100 Polyklonaler Antikörper

FAAP100 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31841-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using FAAP100 Polyclonal antibody (31841-1-AP)

    WB analysis using 31841-1-AP (same clone as 31841-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31841-1-AP (FAAP100 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31841-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31841-1-PBS bindet in WB, Indirect ELISA FAAP100 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FAAP100 fusion protein Ag36385
Vollständiger Name chromosome 17 open reading frame 70
Berechnetes Molekulargewicht93 kDa
Beobachtetes Molekulargewicht100 kDa
GenBank-ZugangsnummerBC117139
Gene symbol C17orf70
Gene ID (NCBI) 80233
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FA core complex associated protein 100 (FAAP100, also known as C17orf70) is a component of the Fanconi anemia (FA), which plays a role in the FA-associated DNA damage response network as well as regulates Fanconi anemia group D2 protein (FANCD2) monoubiquitination and the stability of the FA core complex (PMID: 17396147). FAAP100 deletion leads to FA pathway inactivation, increases TRCs and cotranscriptional R-loops, and contributes to the collapse of replication forks and the generation of DNA damage (PMID: 37580696).