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FAK Monoklonaler Antikörper

FAK Monoklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Maus / IgG2c

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2C5B9

Kat-Nr. : 66258-1-PBS

Synonyme

PTK2, 2C5B9, EC:2.7.10.2, FADK 1, FAK1



Geprüfte Anwendungen

Produktinformation

66258-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA FAK und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG2c
Klonalität Monoklonal
Typ Antikörper
Immunogen FAK fusion protein Ag17966
Vollständiger Name PTK2 protein tyrosine kinase 2
Berechnetes Molekulargewicht 1052 aa, 119 kDa
Beobachtetes Molekulargewicht 110 kDa
GenBank-ZugangsnummerBC028733
Gene symbol FAK
Gene ID (NCBI) 5747
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FAK (Focal adhesion kinase 1) is also named as FAK1, FADK, pp125FAK, FAK and belongs to the protein kinase superfamily. It is a critical tyrosine kinase that modulates cell adhesion, migration, proliferation and survival in response to extracellular signals (PMID:19664602). It also acts as a pivotal signal 'integrator', controlling and coordinating cellular responses that include cell migration, survival, proliferation and, epithelial tissue repair after DNA damage (PMID:20966971). This protein has some isoforms produced by alternative promoter usage and alternative splicing, and the range of the molecular weights are 100-120kD and 40-60kD.