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FAK Monoklonaler Antikörper
FAK Monoklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA
Wirt / Isotyp
Maus / IgG2c
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, IHC, IF/ICC, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
2C5B9
Kat-Nr. : 66258-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
66258-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA FAK und zeigt Reaktivität mit human, Maus, Ratten
Getestete Reaktivität | human, Maus, Ratte |
Wirt / Isotyp | Maus / IgG2c |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | FAK fusion protein Ag17966 |
Vollständiger Name | PTK2 protein tyrosine kinase 2 |
Berechnetes Molekulargewicht | 1052 aa, 119 kDa |
Beobachtetes Molekulargewicht | 110 kDa |
GenBank-Zugangsnummer | BC028733 |
Gene symbol | FAK |
Gene ID (NCBI) | 5747 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
FAK (Focal adhesion kinase 1) is also named as FAK1, FADK, pp125FAK, FAK and belongs to the protein kinase superfamily. It is a critical tyrosine kinase that modulates cell adhesion, migration, proliferation and survival in response to extracellular signals (PMID:19664602). It also acts as a pivotal signal 'integrator', controlling and coordinating cellular responses that include cell migration, survival, proliferation and, epithelial tissue repair after DNA damage (PMID:20966971). This protein has some isoforms produced by alternative promoter usage and alternative splicing, and the range of the molecular weights are 100-120kD and 40-60kD.