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FAM107A Polyklonaler Antikörper

FAM107A Polyklonal Antikörper für IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12176-1-PBS

Synonyme

Down-regulated in renal cell carcinoma 1, DRR1, TU3A

Filter:
  • Immunohistochemistry (IHC) staining of human thyroid cancer tissue using FAM107A Polyclonal antibody (12176-1-AP)

    IHC staining of human thyroid cancer using 12176-1-AP (same clone as 12176-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 12176-1-AP (FAM107A antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12176-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human thyroid cancer tissue using FAM107A Polyclonal antibody (12176-1-AP)

    IHC staining of human thyroid cancer using 12176-1-AP (same clone as 12176-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 12176-1-AP (FAM107A antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12176-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using FAM107A Polyclonal antibody (12176-1-AP)

    IF Staining of HeLa using 12176-1-AP (same clone as 12176-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using FAM107A antibody (12176-1-AP) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 12176-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

12176-1-PBS bindet in IHC, IF/ICC, Indirect ELISA FAM107A und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FAM107A fusion protein Ag2820
Vollständiger Name family with sequence similarity 107, member A
Berechnetes Molekulargewicht 144 aa, 17 kDa
GenBank-ZugangsnummerBC010561
Gene symbol FAM107A
Gene ID (NCBI) 11170
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FAM107A, also named as TU3A, encodes a 144 amino-acid protein, which contains a coiled-coil domain and a nuclear localization signal. FAM107A as a transcription factor regulates some gene transcription and signal transduction in cell. With the exception of peripheral blood cells, FAM107A is widely expressed in normal tissues, but shows significant loss of expression in renal cell carcinomas and frequent loss of expression in cervical, gastric, ovarian and non small cell lung cancers. Transfection of FAM107A mRNA into cancer cell line inhibits cell growth and proliferation, supporting the evidence that the gene functions as an important tumor suppressor.