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FAM172A Polyklonaler Antikörper

FAM172A Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24732-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using FAM172A Polyclonal antibody (24732-1-AP)

    WB analysis using 24732-1-AP (same clone as 24732-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 24732-1-AP (FAM172A antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24732-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human liver tissue using FAM172A Polyclonal antibody (24732-1-AP)

    IHC staining of human liver using 24732-1-AP (same clone as 24732-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 24732-1-AP (FAM172A Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 24732-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human liver tissue using FAM172A Polyclonal antibody (24732-1-AP)

    IHC staining of human liver using 24732-1-AP (same clone as 24732-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 24732-1-AP (FAM172A Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 24732-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

24732-1-PBS bindet in WB, IHC, Indirect ELISA FAM172A und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FAM172A fusion protein Ag20437
Vollständiger Name family with sequence similarity 172, member A
Berechnetes Molekulargewicht 416 aa, 48 kDa
Beobachtetes Molekulargewicht50-55 kDa
GenBank-ZugangsnummerBC020584
Gene symbol FAM172A
Gene ID (NCBI) 83989
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Family with sequence similarity 172 member A (FAM172A), cloned from human aortic tissues, is subsequently observed in human endothelial and vascular smooth muscle cells, and macrophages. As the imbalance of the cell cycle and apoptosis is closely related to the key characteristics of malignant tumors, FAM172A dysregulation is a potential contributing factor in cell transformation. Recently, FAM172A has been reported to take part in the development of several cancers, such as human liver, colorectal and papillary thyroid cancers. Moreover, FAM172A was upregulated by high glucose in a concentration- and time-dependent manner which indicated that FAM172A may be involved in the pathogenesis of diabetic related diseases. FAM172A has 4 isoforms with the molecular mass of 34-36, 43 and 48 kDa. This antibody was detected at 50-55 kDa on SDS-PAGE. (PMID: 31988090, 26637224)