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FAM76B Polyklonaler Antikörper

FAM76B Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32882-1-PBS

Synonyme

Protein FAM76B

Filter:
  • Western Blot (WB) analysis of various lysates using FAM76B Polyclonal antibody (32882-1-AP)

    WB analysis using 32882-1-AP (same clone as 32882-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32882-1-AP (FAM76B antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32882-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32882-1-PBS bindet in WB, Indirect ELISA FAM76B und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FAM76B fusion protein Ag36658
Vollständiger Name family with sequence similarity 76, member B
Berechnetes Molekulargewicht39kDa，339aa
Beobachtetes Molekulargewicht36-39 kDa
GenBank-ZugangsnummerNM_144664.4
Gene symbol FAM76B
Gene ID (NCBI) 143684
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FAM76B is a nuclear protein with a molecular weight of about 39 kDa. Its amino acid sequence is highly conserved, and it is highly similar to FAM76B sequence of rats, mice and zebrafish. The protein contains histidine repeat sequence (poly-His domain) and ubiquitination site of Lys-225. FAM76B inhibits the inflammatory reaction mediated by NF-κB by affecting the cytoplasmic translocation of hnRNPA2B1. The expression of inflammatory factors (such as IL-6) increased significantly in FAM76B gene knockout mice, indicating that FAM76B has anti-inflammatory effect.