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FAM83G Polyklonaler Antikörper

FAM83G Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 29366-1-PBS

Synonyme

Protein FAM83G

Filter:
  • Western Blot (WB) analysis of various lysates using FAM83G Polyclonal antibody (29366-1-AP)

    WB analysis using 29366-1-AP (same clone as 29366-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29366-1-AP (FAM83G antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29366-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

29366-1-PBS bindet in WB, Indirect ELISA FAM83G und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FAM83G fusion protein Ag28925
Vollständiger Name family with sequence similarity 83, member G
Berechnetes Molekulargewicht 91 kDa
Beobachtetes Molekulargewicht100 kDa
GenBank-ZugangsnummerNM_001039999
Gene symbol FAM83G
Gene ID (NCBI) 644815
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FAM83G is a member of the FAM83 protein family, which consists of eight members characterized by sharing a conserved N-terminal domain named DUF1669. This domain is homologous to the phospholipase D catalytic domain but lacks essential catalytic histidine residues, suggesting it is unlikely to have phospholipase activity. FAM83G, in particular, has a consensus motif for serine/threonine protein kinase D1/protein kinase C mu (PKD1/PKCμ) phosphorylation at serine residue 356 (S356), which suggests it may have a unique physiological function among the FAM83 protein family members. Furthermore, FAM83G has been identified as a novel inducer of apoptosis, with its phosphorylation at S356 modulating heat shock protein 27 (HSP27) phosphorylation and apoptosis regulation.