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FAM86A Polyklonaler Antikörper

FAM86A Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32472-1-PBS

Synonyme

EC:2.1.1.-, EEF2KMT, eEF2-KMT, eEF2-lysine methyltransferase, Eukaryotic Elongation Factor 2 Lysine Methyltransferase

Filter:
  • Western Blot (WB) analysis of various lysates using FAM86A Polyclonal antibody (32472-1-AP)

    WB analysis using 32472-1-AP (same clone as 32472-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32472-1-AP (FAM86A antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32472-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32472-1-PBS bindet in WB, Indirect ELISA FAM86A und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FAM86A fusion protein Ag38481
Vollständiger Name family with sequence similarity 86, member A
Beobachtetes Molekulargewicht38 kDa
GenBank-ZugangsnummerBC010084
Gene symbol FAM86A
Gene ID (NCBI) 196483
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FAM86A is a class I lysine methyltransferase (KMT), belonging to the family of protein methyltransferases (KMTs), which produces trimethylation (K525me3) at the Lys525 site of eukaryotic translation elongation factor 2 (EEF2) and promotes the binding of eEF2 to ribosomes, thereby regulating the protein synthesis. (PMID: 38508183) FAM86A is expressed in a highly dependent manner in a variety of human cancer cell lines, suggesting that FAM86A may be a potential target for future anticancer therapy.