FAM96A Polyklonaler Antikörper

FAM96A Polyklonal Antikörper für IF/ICC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IF/ICC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 20776-1-PBS

Synonyme

Protein FAM96A, MIP18 family protein FAM96A, Cytosolic iron-sulfur assembly component 2A, CIAO2A, CIA2A



Geprüfte Anwendungen

Produktinformation

20776-1-PBS bindet in IF/ICC, IP, Indirect ELISA FAM96A und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FAM96A fusion protein Ag14770
Vollständiger Name family with sequence similarity 96, member A
Berechnetes Molekulargewicht 160 aa, 18 kDa
Beobachtetes Molekulargewicht18-21 kDa
GenBank-ZugangsnummerBC008865
Gene symbol FAM96A
Gene ID (NCBI) 84191
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FAM96A (family with sequence similarity 96, member A), also called cytosolic iron-sulfur assembly component 2A (CIAO2A), a recently identified member of the cytosolic iron-sulfur (Fe/S) protein assembly machinery and regulator of cellular iron homeostasis, is a novel pro-apoptotic APAF1-binding protein facilitating the effective induction of cell death via the mitochondrial apoptosis pathway. FAM96A is substantially enriched in macrophages comprised primarily of a DUF59 domain (residues 31-157) and an N-terminal signal peptide (residues 1-27), that is expressed at low levels in tumor cells (PMID: 29399066).