FAM96A Polyklonaler Antikörper
FAM96A Polyklonal Antikörper für IF/ICC, IP, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
IF/ICC, IP, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 20776-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
20776-1-PBS bindet in IF/ICC, IP, Indirect ELISA FAM96A und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | FAM96A fusion protein Ag14770 |
| Vollständiger Name | family with sequence similarity 96, member A |
| Berechnetes Molekulargewicht | 160 aa, 18 kDa |
| Beobachtetes Molekulargewicht | 18-21 kDa |
| GenBank-Zugangsnummer | BC008865 |
| Gene symbol | FAM96A |
| Gene ID (NCBI) | 84191 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
FAM96A (family with sequence similarity 96, member A), also called cytosolic iron-sulfur assembly component 2A (CIAO2A), a recently identified member of the cytosolic iron-sulfur (Fe/S) protein assembly machinery and regulator of cellular iron homeostasis, is a novel pro-apoptotic APAF1-binding protein facilitating the effective induction of cell death via the mitochondrial apoptosis pathway. FAM96A is substantially enriched in macrophages comprised primarily of a DUF59 domain (residues 31-157) and an N-terminal signal peptide (residues 1-27), that is expressed at low levels in tumor cells (PMID: 29399066).





