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FANCA Rekombinanter Antikörper

FANCA Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242600E10

Kat-Nr. : 84923-5-PBS

Synonyme

242600E10, FA, FA1, FAA, FACA

Filter:
  • Western Blot (WB) analysis of various lysates using FANCA Recombinant antibody (84923-5-RR)

    WB analysis using 84923-5-RR (same clone as 84923-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84923-5-RR (FANCA antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84923-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84923-5-RR

    Affinity and Kinetic Characterization of 84923-5-RR

    Biolayer interferometry (BLl) kinetic assays of 84923-5-RR against Human FANCA were performed. The affinity constant is 0.351 nM.

Geprüfte Anwendungen

Produktinformation

84923-5-PBS bindet in WB, Indirect ELISA FANCA und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen FANCA fusion protein Ag2598
Vollständiger Name Fanconi anemia, complementation group A
Berechnetes Molekulargewicht 163 kDa
Beobachtetes Molekulargewicht 163 kDa
GenBank-ZugangsnummerBC008979
Gene symbol FANCA
Gene ID (NCBI) 2175
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FANCA, also named as FAA, FACA and FANCH, is DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. FANCA may be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Defects in FANCA are a cause of Fanconi anemia (FA) which is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. The antibody is specific to isoform1 of FANCA.