FANCA Rekombinanter Antikörper

FANCA Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

242600E10

Kat-Nr. : 84923-5-RR

Synonyme

242600E10, FA, FA1, FAA, FACA

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  WB analysis using 84923-5-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 84923-5-RR (FANCA antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 84923-5-RR

  Biolayer interferometry (BLl) kinetic assays of 84923-5-RR against Human FANCA were performed. The affinity constant is 0.351 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HeLa-Zellen, A549-Zellen, COLO 320-Zellen, HEK-293-Zellen, Jurkat-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

84923-5-RR bindet in WB, ELISA FANCA und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: FANCA fusion protein Ag2598
• Vollständiger Name: Fanconi anemia, complementation group A
• Berechnetes Molekulargewicht: 163 kDa
• Beobachtetes Molekulargewicht: 163 kDa
• GenBank-Zugangsnummer: BC008979
• Gene symbol: FANCA
• Gene ID (NCBI): 2175
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FANCA, also named as FAA, FACA and FANCH, is DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. FANCA may be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Defects in FANCA are a cause of Fanconi anemia (FA) which is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. The antibody is specific to isoform1 of FANCA.