FANCA-Specific Polyklonaler Antikörper

FANCA-Specific Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 19542-1-AP

Synonyme

FA, FA H, FA1, FAA, FACA, FAH, FANCA, FANCA-Specific, FANCH, Fanconi anemia group A protein, Protein FACA

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Galerie der Validierungsdaten

• 

  WB analysis of HeLa using 19542-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 19542-1-AP (FANCA-Specific antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HEK-293 using 19542-1-AP

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 19542-1-AP (FANCA-Specific antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HeLa using 19542-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 19542-1-AP (FANCA-Specific antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HeLa-Zellen, HEK-293-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

19542-1-AP bindet in WB, ELISA FANCA-Specific und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: Fanconi anemia, complementation group A
• Berechnetes Molekulargewicht: 163 kDa
• Beobachtetes Molekulargewicht: 163 kDa
• GenBank-Zugangsnummer: NM_000135
• Gene symbol: FANCA
• Gene ID (NCBI): 2175
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FANCA, also named as FAA, FACA and FANCH, is DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. FANCA may be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Defects in FANCA are a cause of Fanconi anemia (FA) which is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. The antibody is specific to isoform1 of FANCA.