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FANCF Polyklonaler Antikörper

FANCF Polyklonal Antikörper für IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 18060-1-PBS

Synonyme

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  • Immunoprecipitation (IP) experiment of HeLa cells using FANCF Polyclonal antibody (18060-1-AP)

    IP experiment of HeLa using 18060-1-AP (same clone as 18060-1-PBS)

    IP result of anti-FANCF (IP:18060-1-AP, 4ug; Detection:18060-1-AP 1:400) with HeLa cells lysate 1600 ug. This data was developed using the same antibody clone with 18060-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

18060-1-PBS bindet in IP, Indirect ELISA FANCF und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FANCF fusion protein Ag12649
Vollständiger Name Fanconi anemia, complementation group F
Berechnetes Molekulargewicht 374 aa, 42 kDa
Beobachtetes Molekulargewicht36 kDa
GenBank-ZugangsnummerBC093867
Gene symbol FANCF
Gene ID (NCBI) 2188
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The Fanconi anemia complement group F (FANCF) is located on chromosome 11p15, a region enriched in cancer-associated genes. FANCF is known to be involved in DNA repair, and the overexpression of FANCF protein leads to cell proliferation and ultimately to cancer. The epigenetic silencing of FANCF has been reported in several different tumors such as ovaries, bladder, cervical, leukemic, testicular, lung, and oral tumors (PMID: 21915857, 32915143).