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FBXL13 Rekombinanter Antikörper

FBXL13 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251880F12

Kat-Nr. : 86857-1-PBS

Synonyme

DRC6, Dynein regulatory complex subunit 6, FBL13, F-box and leucine-rich repeat protein 13, F-box/LRR-repeat protein 13

Filter:
  • Western Blot (WB) analysis of various lysates using FBXL13 Recombinant monoclonal antibody (86857-1-RR)

    WB analysis using 86857-1-RR (same clone as 86857-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86857-1-RR (FBXL13 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86857-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86857-1-PBS bindet in WB, Indirect ELISA FBXL13 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen FBXL13 fusion protein Ag10903
Vollständiger Name F-box and leucine-rich repeat protein 13
Berechnetes Molekulargewicht 707 aa, 81 kDa
Beobachtetes Molekulargewicht84 kDa
GenBank-ZugangsnummerBC031285
Gene symbol FBXL13
Gene ID (NCBI) 222235
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FBXL13, also known as F-box and leucine-rich repeat protein 13, is a human protein-coding gene located on chromosome 7q22.1. It is a member of the F-box protein family, characterized by an approximately 40-amino acid F-box motif. FBXL13 is part of the SCF-type E3 ubiquitin ligase complex, which plays a role in protein ubiquitination and degradation. The gene has multiple isoforms, including 84 kDa, 81 kDa, 79 kDa, and 53 kDa variants. While its specific function within the complex is not fully understood, FBXL13 has been implicated in regulating centrosome homeostasis and cell migration by directing the proteolysis of CEP192. Additionally, it may play a role in circadian rhythms by ubiquitinating and mediating the degradation of cryptochrome proteins.