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FBXO16 Polyklonaler Antikörper

FBXO16 Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32063-1-PBS

Synonyme

F box only protein 16, F box protein 16, FBX16

Filter:
  • Western Blot (WB) analysis of various lysates using FBXO16 Polyclonal antibody (32063-1-AP)

    WB analysis using 32063-1-AP (same clone as 32063-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32063-1-AP (FBXO16 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32063-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of T-47D cells using FBXO16 Polyclonal antibody (32063-1-AP)

    IP experiment of T-47D using 32063-1-AP (same clone as 32063-1-PBS)

    IP result of anti-FBXO16 (IP:32063-1-AP, 4ug; Detection:32063-1-AP 1:1000) with T-47D cells lysate 1120 ug. This data was developed using the same antibody clone with 32063-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32063-1-PBS bindet in WB, IP, Indirect ELISA FBXO16 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FBXO16 fusion protein Ag36230
Vollständiger Name F-box protein 16
Berechnetes Molekulargewicht 292 aa, 35 kDa
Beobachtetes Molekulargewicht35 kDa
GenBank-ZugangsnummerBC074986
Gene symbol FBXO16
Gene ID (NCBI) 157574
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FBXO16 is a member of the F-box protein family, which functions as a substrate recognition subunit of the SCF (Skp1-Cullin-F-box) E3 ubiquitin ligase complex. High expression levels of FBXO16 are associated with better prognosis in cancer patients. For example, in ovarian cancer, patients with higher FBXO16 expression tend to have a more favorable outcome (PMID: 34333526). This suggests that FBXO16 could serve as a potential biomarker for cancer prognosis and therapeutic targeting.