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FBXO32 Polyklonaler Antikörper

FBXO32 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 28541-1-PBS

Synonyme

Filter:
  • Immunohistochemistry (IHC) staining of mouse skeletal muscle tissue using FBXO32 Polyclonal antibody (28541-1-AP)

    IHC staining of mouse skeletal muscle using 28541-1-AP (same clone as 28541-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 28541-1-AP (FBXO32 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28541-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse skeletal muscle tissue using FBXO32 Polyclonal antibody (28541-1-AP)

    IHC staining of mouse skeletal muscle using 28541-1-AP (same clone as 28541-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 28541-1-AP (FBXO32 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28541-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

28541-1-PBS bindet in IHC, Indirect ELISA FBXO32 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FBXO32 fusion protein Ag29410
Vollständiger Name F-box protein 32
Berechnetes Molekulargewicht 355 aa, 42 kDa
GenBank-ZugangsnummerBC024030
Gene symbol FBXO32
Gene ID (NCBI) 114907
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FBXO32 (F box only protein 32), also known as Atrogin 1 or MAFbx, is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif F-box. This protein is an E3 ubiquitin ligase that is markedly up-regulated in muscle atrophy. FBXO32 is thus a potential drug target for the treatment of muscle atrophy. Some data support that FBXO32 may play an important role in tumorigenesis. Recent study reveal that FBXO32 targets the oncogenic protein c-Myc for ubiquitination and degradation through the proteasome pathway.