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FBXO33 Polyklonaler Antikörper

FBXO33 Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 23381-1-PBS

Synonyme

FBX33, F-box only protein 33, c14_5247, BMND12

Filter:
  • Western Blot (WB) analysis of various lysates using FBXO33 Polyclonal antibody (23381-1-AP)

    WB analysis using 23381-1-AP (same clone as 23381-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 23381-1-AP (FBXO33 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23381-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of MCF-7 cells using FBXO33 Polyclonal antibody (23381-1-AP)

    IF Staining of MCF-7 using 23381-1-AP (same clone as 23381-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using FBXO33 antibody (23381-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 23381-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

23381-1-PBS bindet in WB, IF/ICC, Indirect ELISA FBXO33 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FBXO33 fusion protein Ag20055
Vollständiger Name F-box protein 33
Berechnetes Molekulargewicht 555 aa, 63 kDa
Beobachtetes Molekulargewicht63 kDa
GenBank-ZugangsnummerBC068566
Gene symbol FBXO33
Gene ID (NCBI) 254170
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

F-box Only Protein 33 (FBXO33) is a typical member of the F-box protein family with E3 ligase function. FBXO33 can regulate the ubiquitination and solubility of polyglutamine disease proteins, potentially serving as a target for treating type 3 spinocerebellar ataxia. FBXO33 ligase interferes with YB-1-mediated functions by binding and ubiquitinating the multifunctional regulator Y-box-binding protein 1 (YB-1)/dbpB/p50, leading to proteasomal degradation (PMID: 39206900). The calculated molecular weight of FBXO33 is 63 kDa.