FBXO38 Polyklonaler Antikörper

FBXO38 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31282-1-PBS

Synonyme

SP329, MOKA, Fbx38, F box protein 38, F box only protein 38

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  WB analysis using 31282-1-AP (same clone as 31282-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31282-1-AP (FBXO38 antibody) at dilution of 1:15000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31282-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

31282-1-PBS bindet in WB, Indirect ELISA FBXO38 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: FBXO38 fusion protein Ag35444
• Vollständiger Name: F-box protein 38
• Berechnetes Molekulargewicht: 134kDa，1188aa
• Beobachtetes Molekulargewicht: 140 kDa, 107 kDa
• GenBank-Zugangsnummer: XM_005268513.1
• Gene symbol: FBXO38
• Gene ID (NCBI): 81545
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

F-box containing protein 38 (FBXO38; also known as MoKA) is a substrate receptor for SKP1-CUL1-dependent ubiquitin ligase (SCF). Initially, it was discovered as a modulator of transcription factor Krüppel-like factor 7 (KLF7) activity (PMID: 14729953). In addition, FBXO38 stability is controlled via ubiquitin-specific peptidase 7 (USP7), and FBXO38 protein expression was shown to be required for proper cytokinesis (PMID: 30804394). However, as a ubiquitin ligase, SCFFBXO38 is still insufficiently characterized. So far, the only potential substrate identified is programmed cell death 1 (PD-1) (PMID: 30487606, PMID: 35813202).