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FCER1G Rekombinanter Antikörper

FCER1G Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Hausschwein, human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242829E3

Kat-Nr. : 85390-2-PBS

Synonyme

242829E3, Fc epsilon RI gamma, Fc receptor gamma-chain, Fc-epsilon RI-gamma, FceRI gamma

Filter:
  • Western Blot (WB) analysis of various lysates using FCER1G Recombinant antibody (85390-2-RR)

    WB analysis using 85390-2-RR (same clone as 85390-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85390-2-RR (FCER1G antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85390-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85390-2-RR

    Affinity and Kinetic Characterization of 85390-2-RR

    Biolayer interferometry (BLl) kinetic assays of 85390-2-RR against Human FCER1G were performed. The affinity constant is 1.16 nM.

Geprüfte Anwendungen

Produktinformation

85390-2-PBS bindet in WB, Indirect ELISA FCER1G und zeigt Reaktivität mit Hausschwein, human, Maus

Getestete Reaktivität Hausschwein, human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen FCER1G fusion protein Ag4442
Vollständiger Name Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
Berechnetes Molekulargewicht 87 aa, 10 kDa
Beobachtetes Molekulargewicht10 kDa
GenBank-ZugangsnummerBC033872
Gene symbol FcRγ
Gene ID (NCBI) 2207
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FCER1G (Fc receptor gamma-chain, FcRgamma), also known as Fc-epsilon RI-gamma, or IgE Fc receptor subunit gamma (FceRI gamma), is a component of the high-affinity immunoglobulin E (IgE) receptor (Fc epsilon RI) which is a tetrameric complex of one alpha subunit, one beta subunit, and two disulfide-linked gamma subunits (PMID: 2146219; 2531187). Fc epsilon RI is present exclusively on mast cells and basophils, mediating allergic inflammatory signaling (PMID: 17438574). FCER1G is widely expressed and contains an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various immunoreceptors (PMID: 19098920).