FCGR3A/CD16a Polyklonaler Antikörper
FCGR3A/CD16a Polyklonal Antikörper für WB, IF-P, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
WB, IF-P, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 30356-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
30356-1-PBS bindet in WB, IF-P, Indirect ELISA FCGR3A/CD16a und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | FCGR3A/CD16a fusion protein Ag1281 |
| Vollständiger Name | Fc fragment of IgG, low affinity IIIa, receptor (CD16a) |
| Berechnetes Molekulargewicht | 29 kDa |
| Beobachtetes Molekulargewicht | 65-70 kDa |
| GenBank-Zugangsnummer | BC036723 |
| Gene symbol | CD16a |
| Gene ID (NCBI) | 2214 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
CD16 is a low affinity Fc receptor. It has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B. In humans, FcγRIIIa/CD16a is a type I transmembrane receptor expressed on macrophages and NK cells. FcγRIIIb/CD16b is a GPI-linked Fc-receptor highly expressed on neutrophils. The two proteins differ by only four amino acid residues in the mature proteins(PMID: 30361439). FCGR3A has a calculated molecular weight of 29 kDa, with an apparent molecular weight of 50-80 kDa due to extensive glycosylation (PMID: 30655272; PMID: 27914599). The antibody is specific for FCGR3A/CD16a.





