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FCRL1 Polyklonaler Antikörper

FCRL1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 33184-1-PBS

Synonyme

CD307a, Fc receptor-like protein 1, FcRH1, FcR-like protein 1, IFGP family protein 1

Filter:
  • Western Blot (WB) analysis of various lysates using FCRL1 Polyclonal antibody (33184-1-AP)

    WB analysis using 33184-1-AP (same clone as 33184-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33184-1-AP (FCRL1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33184-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

33184-1-PBS bindet in WB, Indirect ELISA FCRL1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FCRL1 fusion protein Eg3713
Vollständiger Name Fc receptor-like 1
Berechnetes Molekulargewicht 429 aa, 47 kDa
Beobachtetes Molekulargewicht47 kDa
GenBank-ZugangsnummerBC033690
Gene symbol FCRL1
Gene ID (NCBI) 115350
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Fc receptor-like protein 1 (FCRL1) is a type I transmembrane glycoprotein that plays a crucial role in regulating B-cell receptor (BCR)-mediated signaling responses (PMID:15479727). It contains intracellular tyrosine-based motifs that can modulate BCR signaling, leading to changes in calcium flux, proliferation, and antibody production (PMID: 37822931). FCRL1 is involved in regulating B-cell development and activation, with its signaling pathways influencing ERK activation through interactions with proteins such as GRB2. This regulation is essential for maintaining B-cell homeostasis and preventing the development of autoreactive B cells (PMID: 34697226).