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FCRL1 Rekombinanter Antikörper

FCRL1 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

251080E1

Kat-Nr. : 98557-1-PBS

Synonyme

CD307a, Fc receptor-like protein 1, FcRH1, FcR-like protein 1, IFGP family protein 1

Filter:
  • Flow cytometry (FC) experiment of human PBMCs using Anti-Human FCRL1 Rabbit Recombinant Antibody (98557-1-RR)

    FC experiment of human PBMCs using 98557-1-RR (same clone as 98557-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human FCRL1 Rabbit RecAb (98557-1-RR, Clone: 251080E1) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98557-1-PBS in a different storage buffer formulation.

  • Flow cytometry (FC) experiment of human PBMCs using Anti-Human FCRL1 Rabbit Recombinant Antibody (98557-1-RR)

    FC experiment of human PBMCs using 98557-1-RR (same clone as 98557-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human FCRL1 Rabbit RecAb (98557-1-RR, Clone: 251080E1) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98557-1-PBS in a different storage buffer formulation.

  • Flow cytometry (FC) experiment of Transfected CHO using Anti-Human FCRL1 Rabbit Recombinant Antibody (98557-1-RR)

    FC experiment of Transfected CHO using 98557-1-RR (same clone as 98557-1-PBS)

    1x10^6 CHO Cells (left) or FCRL1(CD307a)-transfected CHO Cells (right) were surface stained with 0.25 ug Anti-Human FCRL1 Rabbit RecAb (98557-1-RR, Clone: 251080E1) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98557-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

98557-1-PBS bindet in FC FCRL1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen FCRL1 fusion protein Eg3713
Vollständiger Name Fc receptor-like 1
Berechnetes Molekulargewicht 429 aa, 47 kDa
GenBank-ZugangsnummerBC033690
Gene symbol FCRL1
Gene ID (NCBI) 115350
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C.

Hintergrundinformationen

Fc receptor-like protein 1 (FCRL1) is a type I transmembrane glycoprotein that plays a crucial role in regulating B-cell receptor (BCR)-mediated signaling responses (PMID:15479727). It contains intracellular tyrosine-based motifs that can modulate BCR signaling, leading to changes in calcium flux, proliferation, and antibody production (PMID: 37822931). FCRL1 is involved in regulating B-cell development and activation, with its signaling pathways influencing ERK activation through interactions with proteins such as GRB2. This regulation is essential for maintaining B-cell homeostasis and preventing the development of autoreactive B cells (PMID: 34697226).