FDPS Polyklonaler Antikörper

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FDPS Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 16129-1-PBS

Synonyme

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  WB analysis using 16129-1-AP (same clone as 16129-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 16129-1-AP (FDPS antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16129-1-PBS in a different storage buffer formulation.

• 

  WB analysis of A431 using 16129-1-AP (same clone as 16129-1-PBS)

  WB result of FDPS antibody (16129-1-AP; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-FDPS transfected A431 cells. This data was developed using the same antibody clone with 16129-1-PBS in a different storage buffer formulation.

• 

  WB analysis of rat liver using 16129-1-AP (same clone as 16129-1-PBS)

  rat liver tissue were subjected to SDS PAGE followed by western blot with 16129-1-AP (FDPS antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16129-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human cerebellum using 16129-1-AP (same clone as 16129-1-PBS)

  human cerebellum tissue were subjected to SDS PAGE followed by western blot with 16129-1-AP (FDPS antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16129-1-PBS in a different storage buffer formulation.

• 

  IP experiment of mouse liver using 16129-1-AP (same clone as 16129-1-PBS)

  IP result of anti-FDPS (IP:16129-1-AP, 4ug; Detection:16129-1-AP 1:1000) with mouse liver tissue lysate 4000ug. This data was developed using the same antibody clone with 16129-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

16129-1-PBS bindet in WB, IP, Indirect ELISA FDPS und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: FDPS fusion protein Ag9115
• Vollständiger Name: farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
• Berechnetes Molekulargewicht: 419 aa, 48 kDa
• Beobachtetes Molekulargewicht: 39-41 kDa
• GenBank-Zugangsnummer: BC010004
• Gene symbol: FDPS
• Gene ID (NCBI): 2224
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FPPS (also known as FDPS) is a key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. The expression of FPPS was elevated in prostate tumor cell lines, indicating its potential role in prostate cancer progression.