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FDX1L Polyklonaler Antikörper

FDX1L Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32790-1-PBS

Synonyme

Adrenodoxin-like protein, FDX2, Ferredoxin-1-like protein, Ferredoxin-2, mitochondrial

Filter:
  • Western Blot (WB) analysis of various lysates using FDX1L Polyclonal antibody (32790-1-AP)

    WB analysis using 32790-1-AP (same clone as 32790-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32790-1-AP (FDX1L antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32790-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32790-1-PBS bindet in WB, Indirect ELISA FDX1L und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FDX1L fusion protein Ag37104
Vollständiger Name ferredoxin 1-like
Berechnetes Molekulargewicht183 aa, 20 kDa
Beobachtetes Molekulargewicht21 kDa
GenBank-ZugangsnummerBC063460
Gene symbol FDX1L
Gene ID (NCBI) 112812
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FDX1L (ferredoxin 1-like) is a gene encoding mitochondrial protein whose primary function is to participate in the biosynthesis of iron-sulfur clusters (Fe-S clusters). FDX1L is closely related to the assembly of iron-sulfur clusters and is the second component in the biosynthesis mechanism of iron-sulfur clusters. Studies have shown that FDX1L is widely expressed in human cells, especially in the central nervous system. In addition, mutations in FDX1L can lead to mitochondrial myopathy, manifested by a significant reduction in the activity of respiratory chain complexes I, II, and III. The function of FDX1L is different from that of FDX1 (ferredoxin 1). FDX1 is mainly involved in the synthesis of steroid hormones, while FDX1L focuses on the biosynthesis of iron-sulfur clusters. This functional difference allows FDX1L to play an important role in maintaining homeostasis of iron-sulfur clusters in the cell.