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FDXR Rekombinanter Antikörper

FDXR Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251211C10

Kat-Nr. : 86431-1-PBS

Synonyme

ADR, ADXR, EC:1.18.1.6, Ferredoxin reductase, Ferredoxin--NADP(+) reductase

Filter:
  • Western Blot (WB) analysis of various lysates using FDXR Recombinant antibody (86431-1-RR)

    WB analysis using 86431-1-RR (same clone as 86431-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86431-1-RR (FDXR antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86431-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86431-1-RR

    Affinity and Kinetic Characterization of 86431-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86431-1-RR against Human FDXR were performed. The affinity constant is 77.5 pM.

Geprüfte Anwendungen

Produktinformation

86431-1-PBS bindet in WB, Indirect ELISA FDXR und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen FDXR fusion protein Ag7145
Vollständiger Name ferredoxin reductase
Berechnetes Molekulargewicht 54 kDa
Beobachtetes Molekulargewicht50 kDa
GenBank-ZugangsnummerBC063493
Gene symbol FDXR
Gene ID (NCBI) 2232
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Ferredoxin reductase (FDXR, also known as adrenodoxin reductase) is a mitochondrial membrane-associated flavoprotein. One of its functions is to transfer electrons from NADPH to the two human ferredoxin proteins, FDX1 and FDX2. FDXR is expressed in all tissues with the highest expression in tissues such as the adrenal cortex, that specialize in steroid hormone synthesis. Functionally, FDXR is suggested to be involved in various Functionally, FDXR is suggested to be involved in various. Notably, recent studies have shown that FDXR mutations are associated with mitochondrial disorders, probably due to its role in iron-sulfur cluster protein biosynthesis (PMID: 32304229). FDXR has 7 isoforms with the molecular weight of 48-58 kDa.