FGD6 Rekombinanter Antikörper

FGD6 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

240260A6

Kat-Nr. : 83296-4-RR

Synonyme

Zinc finger FYVE domain-containing protein 24, ZFYVE24, FYVE, RhoGEF and PH domain-containing protein 6, 240260A6

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  WB analysis using 83296-4-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 83296-4-RR (FGD6 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 83296-4-RR

  Biolayer interferometry (BLl) kinetic assays of 83296-4-RR against Human FGD6 were performed. The affinity constant is 10.7 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: K-562-Zellen, A549-Zellen, HEK-293-Zellen, HeLa-Zellen, Jurkat-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

83296-4-RR bindet in WB, ELISA FGD6 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: FGD6 fusion protein Ag22211
• Vollständiger Name: FYVE, RhoGEF and PH domain containing 6
• Berechnetes Molekulargewicht: 1430 aa, 161 kDa
• Beobachtetes Molekulargewicht: 161 kDa
• GenBank-Zugangsnummer: BC013319
• Gene symbol: FGD6
• Gene ID (NCBI): 55785
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FGD6, also known as ZFYVE24, is localized on the Homo sapiens chromosome 12q22 and consists of 1,400 amino acids. Previous studies have reported that variations in FGD6 increase individual susceptibility to polypoidal choroidal vasculopathy. It was also demonstrated that FGD6 coordinates cell polarity and endosomal membrane recycling in osteoclasts by regulating the assembly of different actin-based protein networks and activating Cdc42 at different locations.