FGFBP1 Polyklonaler Antikörper

FGFBP1 Polyklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(7)

Kat-Nr. : 25006-1-AP

Synonyme

17 kDa HBGF binding protein, 17 kDa HBGF-binding protein, 17 kDa heparin-binding growth factor-binding protein, FGF binding protein 1, FGF BP

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  IHC staining of human skin cancer using 25006-1-AP

  Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 25006-1-AP (FGFBP1 antibody) at dilution of 1:200 (under 10x lens).

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  IHC staining of human skin cancer using 25006-1-AP

  Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 25006-1-AP (FGFBP1 antibody) at dilution of 1:200 (under 40x lens).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IHC: humanes Hautkrebsgewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

• Immunhistochemie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 6 publications below
• IHC: See 4 publications below
• IF: See 1 publications below

Produktinformation

25006-1-AP bindet in WB, IHC, IF, ELISA FGFBP1 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: FGFBP1 fusion protein Ag6357
• Vollständiger Name: fibroblast growth factor binding protein 1
• Berechnetes Molekulargewicht: 26 kDa
• GenBank-Zugangsnummer: BC003628
• Gene symbol: FGFBP1
• Gene ID (NCBI): 9982
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FGFBP1, also named as HBP17, is prominent for its role as the chaperone for fibroblast growth factor-2 (FGF-2), which plays a crucial role in angiogenesis as well as promoting tumor growth. HBp17/FGFBP-1 has been proposed as a candidate biomarker for a number of cancers since it is frequently found to be elevated in many cancer types including in the tissue and cell lines of oral squamous cell carcinomas (OSCC).

Publikationen

Species	Application	Title
mouse	IF	Mol Cell; A transient transcriptional activation governs unpolarized-to-polarized morphogenesis during embryo implantation; Authors - Xuehui Lyu
human	WB,IHC	Front Immunol; FGFBP1 as a potential biomarker predicting bacillus Calmette-Guérin response in bladder cancer; Authors - Fei Li
mouse	WB,IHC	Am J Cancer Res; Type-2 11β-hydroxysteroid dehydrogenase promotes the metastasis of colorectal cancer via the Fgfbp1-AKT pathway.; Authors - Jin Chen ; KD Validated
human	WB,IHC	Transl Oncol; Identification of metastasis-associated exoDEPs in colorectal cancer using label-free proteomics.; Authors - Xinlu Liu
mouse,human	WB,IHC	Front Pharmacol; B4 suppresses lymphoma progression by inhibiting fibroblast growth factor binding protein 1 through intrinsic apoptosis; Authors - Krishnapriya M Varier
human	WB	Pharm Biol; Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro; Authors - Yang Yang