FGFR1 Polyklonaler Antikörper

FGFR1 Polyklonal Antikörper für IHC, IF/ICC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IHC, IF/ICC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30358-1-PBS

Synonyme

bFGF R 1, BFGFR, bFGF-R-1, CD331, CEK

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  IP experiment of SH-SY5Y using 30358-1-AP (same clone as 30358-1-PBS)

  IP result of anti-FGFR1 (IP:30358-1-AP, 4ug; Detection:30358-1-AP 1:300) with SH-SY5Y cells lysate 770 ug. This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of rat kidney using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IHC staining of rat kidney using 30358-1-AP (same clone as 30358-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 30358-1-AP (FGFR1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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  IF Staining of SH-SY5Y using 30358-1-AP (same clone as 30358-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using FGFR1 antibody (30358-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 30358-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

30358-1-PBS bindet in IHC, IF/ICC, IP, Indirect ELISA FGFR1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: fibroblast growth factor receptor 1
• Berechnetes Molekulargewicht: 820 aa, 91 kDa
• Beobachtetes Molekulargewicht: 80 kDa, 95 kDa, 105 kDa
• GenBank-Zugangsnummer: BC018128
• Gene symbol: FGFR1
• Gene ID (NCBI): 2260
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Fibroblast growth factor receptor 1 (FGFR1) is a tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors. FGFR1 has been implicated in diverse biological processes including embryonic development, cell proliferation, differentiation, migration, and tumorigenesis. Mutations in the FGFR1 gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer, and autosomal dominant Kallmann syndrome. Alternatively spliced variants that encode different protein isoforms have been described.