FGFR1OP Polyklonaler Antikörper

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• KD/KO Validated

FGFR1OP Polyklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11343-1-PBS

Synonyme

FOP, FGFR1 oncogene partner, CEP43, Centrosomal protein 43

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  WB analysis using 11343-1-AP (same clone as 11343-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 11343-1-AP (FGFR1OP antibody) at dilution of 1:15000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11343-1-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 11343-1-AP (same clone as 11343-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 11343-1-AP (FGFR1OP Antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11343-1-PBS in a different storage buffer formulation.

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  WB analysis of U-937 using 11343-1-AP (same clone as 11343-1-PBS)

  U-937 cells were subjected to SDS PAGE followed by western blot with 11343-1-AP (FGFR1OP Antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11343-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse heart using 11343-1-AP (same clone as 11343-1-PBS)

  mouse heart tissue were subjected to SDS PAGE followed by western blot with 11343-1-AP (FGFR1OP antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11343-1-PBS in a different storage buffer formulation.

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  IHC staining of human lymphoma using 11343-1-AP (same clone as 11343-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma using 11343-1-AP (FGFR1OP antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11343-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 11343-1-AP (same clone as 11343-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using FGFR1OP antibody (11343-1-AP) at dilution of 1:100 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 11343-1-PBS in a different storage buffer formulation.

• 

  IF Staining of HEK-293 using 11343-1-AP (same clone as 11343-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed HEK-293 cells using FGFR1OP antibody (11343-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 11343-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

11343-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA FGFR1OP und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: FGFR1OP fusion protein Ag1891
• Vollständiger Name: FGFR1 oncogene partner
• Berechnetes Molekulargewicht: 43 kDa
• Beobachtetes Molekulargewicht: 50 kDa
• GenBank-Zugangsnummer: BC011902
• Gene symbol: FGFR1OP
• Gene ID (NCBI): 11116
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The fibroblast growth factor receptor 1 oncogene partner (FGFR1OP), FOP, is a centrosomal protein that is involved in the anchoring of microtubules to subcellular structures. Three isoforms have been produced by alternative splicing. A chromosomal aberration involving FGFR1OP may be a cause of stem cell myeloproliferative disorder (MPD). MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma and progresses to acute myeloid leukemia.