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FHIT Polyklonaler Antikörper

FHIT Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13362-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using FHIT Polyclonal antibody (13362-1-AP)

    WB analysis using 13362-1-AP (same clone as 13362-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13362-1-AP (FHIT antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13362-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

13362-1-PBS bindet in WB, Indirect ELISA FHIT und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen FHIT fusion protein Ag4181
Vollständiger Name fragile histidine triad gene
Berechnetes Molekulargewicht 147 aa, 17 kDa
Beobachtetes Molekulargewicht15-17 kDa
GenBank-ZugangsnummerBC032336
Gene symbol FHIT
Gene ID (NCBI) 2272
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The candidate tumor suppressor gene, FHIT(Fragile histidine triad protein), encompasses the common human chromosomal fragile site at 3p14.2, the hereditary renal cancer translocation breakpoint, and cancer cell homozygous deletions. Fhit hydrolyzes dinucleotide 5',5'''-P1,P3-triphosphate in vitro and mutation of a central histidine abolishes hydrolase activity(PMID:9391102). FHIT has a major role in regulating beta-catenin-mediated gene transcription.