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FHIT Monoklonaler Antikörper

FHIT Monoklonal Antikörper für Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

4D6G1

Kat-Nr. : 66086-1-PBS

Synonyme

Adenosine 5'-monophosphoramidase FHIT, Adenylylsulfatase, Adenylylsulfate-ammonia adenylyltransferase, AP3A hydrolase, AP3Aase

Filter:
  • Western Blot (WB) analysis of K-562 cells using FHIT Monoclonal antibody (66086-1-Ig)

    WB analysis of K-562 using 66086-1-Ig (same clone as 66086-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 66086-1-Ig (FHIT antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66086-1-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP51232-1

    Cytometric bead array standard curve of MP51232-1

    Cytometric bead array standard curve of MP51232-1, FHIT Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60833-1-PBS. Detection antibody: 66086-1-PBS. Standard:Ag14471. Range: 0.391-100 ng/mL.

Geprüfte Anwendungen

Produktinformation

66086-1-PBS bindet in Cytometric bead array, Indirect ELISA FHIT und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen FHIT fusion protein Ag14471
Vollständiger Name fragile histidine triad gene
Berechnetes Molekulargewicht 147 aa, 17 kDa
Beobachtetes Molekulargewicht 17 kDa
GenBank-ZugangsnummerBC032336
Gene symbol FHIT
Gene ID (NCBI) 2272
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The candidate tumor suppressor gene, FHIT(Fragile histidine triad protein), encompasses the common human chromosomal fragile site at 3p14.2, the hereditary renal cancer translocation breakpoint, and cancer cell homozygous deletions. Fhit hydrolyzes dinucleotide 5',5'''-P1,P3-triphosphate in vitro and mutation of a central histidine abolishes hydrolase activity(PMID:9391102). FHIT has a major role in regulating beta-catenin-mediated gene transcription.